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Research Article

Pathogen Recognition Receptor Signaling Accelerates Phosphorylation-Dependent Degradation of IFNAR1

  • Juan Qian equal contributor,

    equal contributor Contributed equally to this work with: Juan Qian, Hui Zheng

    Affiliation: Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    X
  • Hui Zheng equal contributor,

    equal contributor Contributed equally to this work with: Juan Qian, Hui Zheng

    Affiliation: Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    X
  • Wei-Chun HuangFu,

    Affiliation: Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    X
  • Jianghuai Liu,

    Affiliation: Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    X
  • Christopher J. Carbone,

    Affiliation: Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    X
  • N. Adrian Leu,

    Affiliation: Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    X
  • Darren P. Baker,

    Affiliation: BiogenIdec, Cambridge, Massachusetts, United States of America

    X
  • Serge Y. Fuchs mail

    syfuchs@vet.upenn.edu

    Affiliation: Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    X
  • Published: June 09, 2011
  • DOI: 10.1371/journal.ppat.1002065

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