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Research Article

Glycosaminoglycan Binding Facilitates Entry of a Bacterial Pathogen into Central Nervous Systems

  • Yung-Chi Chang,

    Affiliations: Glycobiology Research and Training Center, University of California, San Diego, La Jolla, California, United States of America, Department of Pediatrics, University of California, San Diego, La Jolla, California, United States of America

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  • Zhipeng Wang,

    Affiliations: Channing Laboratory, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Children's Hospital, Boston, Massachusetts, United States of America

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  • Lindsay A. Flax,

    Affiliation: Channing Laboratory, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

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  • Ding Xu,

    Affiliations: Glycobiology Research and Training Center, University of California, San Diego, La Jolla, California, United States of America, Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, California, United States of America

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  • Jeffrey D. Esko,

    Affiliations: Glycobiology Research and Training Center, University of California, San Diego, La Jolla, California, United States of America, Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, California, United States of America

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  • Victor Nizet mail,

    vnizet@ucsd.edu (VN); mbaron@partners.org (MJB)

    Affiliations: Glycobiology Research and Training Center, University of California, San Diego, La Jolla, California, United States of America, Department of Pediatrics, University of California, San Diego, La Jolla, California, United States of America, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, California, United States of America, Rady Children's Hospital, San Diego, California, United States of America

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  • Miriam J. Baron mail

    vnizet@ucsd.edu (VN); mbaron@partners.org (MJB)

    Affiliations: Channing Laboratory, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Published: June 23, 2011
  • DOI: 10.1371/journal.ppat.1002082

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