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Research Article

Granzyme B Inhibits Vaccinia Virus Production through Proteolytic Cleavage of Eukaryotic Initiation Factor 4 Gamma 3

  • Marcelo Marcet-Palacios,

    Affiliation: University of Alberta, Department of Biochemistry, Edmonton, Alberta, Canada

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  • Brenda Lee Duggan,

    Affiliation: University of Alberta, Department of Biochemistry, Edmonton, Alberta, Canada

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  • Irene Shostak,

    Affiliation: University of Alberta, Department of Biochemistry, Edmonton, Alberta, Canada

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  • Michele Barry,

    Affiliation: University of Alberta, Department of Medical Microbiology and Immunology, Edmonton, Alberta, Canada

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  • Tracy Geskes,

    Affiliation: University of Alberta, Department of Biochemistry, Edmonton, Alberta, Canada

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  • John A. Wilkins,

    Affiliation: University of Manitoba, Manitoba Centre for Proteomics & Systems Biology, Winnipeg, Manitoba, Canada

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  • Akiko Yanagiya,

    Affiliation: McGill University, Department of Biochemistry, Montreal, Quebec, Canada

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  • Nahum Sonenberg,

    Affiliation: McGill University, Department of Biochemistry, Montreal, Quebec, Canada

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  • R. Chris Bleackley mail

    chris.bleackley@ualberta.ca

    Affiliation: University of Alberta, Department of Biochemistry, Edmonton, Alberta, Canada

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  • Published: December 15, 2011
  • DOI: 10.1371/journal.ppat.1002447

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