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Research Article

Identification and in vitro Analysis of the GatD/MurT Enzyme-Complex Catalyzing Lipid II Amidation in Staphylococcus aureus

  • Daniela Münch,

    Affiliation: Institute of Medical Microbiology, Immunology and Parasitology – Pharmaceutical Microbiology Section, University of Bonn, Bonn, Germany

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  • Terry Roemer,

    Affiliation: Department of Infectious Diseases, Merck Research Laboratories, Merck & Co., Kenilworth, New Jersey, United States of America

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  • Sang Ho Lee,

    Affiliation: Department of Infectious Diseases, Merck Research Laboratories, Merck & Co., Kenilworth, New Jersey, United States of America

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  • Marianne Engeser,

    Affiliation: Kekulé Institute for Organic Chemistry and Biochemistry, University of Bonn, Bonn, Germany

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  • Hans Georg Sahl,

    Affiliation: Institute of Medical Microbiology, Immunology and Parasitology – Pharmaceutical Microbiology Section, University of Bonn, Bonn, Germany

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  • Tanja Schneider mail

    tanja@microbiology-bonn.de

    Affiliation: Institute of Medical Microbiology, Immunology and Parasitology – Pharmaceutical Microbiology Section, University of Bonn, Bonn, Germany

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  • Published: January 26, 2012
  • DOI: 10.1371/journal.ppat.1002509

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Identification of Genetic Determinants and Enzymes Involved with the Amidation of Glutamic Acid Residues in the Peptidoglycan of Staphylococcus aureus

Teresa A. Figueiredo, Rita G. Sobral, Ana Madalena Ludovice, João Manuel Feio de Almeida, Nhat K. Bui, Waldemar Vollmer, Hermínia de Lencastre, Alexander Tomasz
Research Article | published 26 Jan 2012 | PLOS Pathogens
doi:10.1371/journal.ppat.1002508