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Research Article

ADCC Develops Over Time during Persistent Infection with Live-Attenuated SIV and Is Associated with Complete Protection against SIVmac251 Challenge

  • Michael D. Alpert,

    Affiliation: Department of Microbiology and Immunobiology, Harvard Medical School, New England Primate Research Center, Southborough, Massachusetts, United States of America

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  • Jackson D. Harvey,

    Affiliation: Department of Microbiology and Immunobiology, Harvard Medical School, New England Primate Research Center, Southborough, Massachusetts, United States of America

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  • W. Anderson Lauer,

    Affiliation: Department of Microbiology and Immunobiology, Harvard Medical School, New England Primate Research Center, Southborough, Massachusetts, United States of America

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  • R. Keith Reeves,

    Affiliation: Immunology Division, Harvard Medical School, New England Primate Research Center, Southborough, Massachusetts, United States of America

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  • Michael Piatak Jr.,

    Affiliation: SAIC Frederick, National Cancer Institute at Frederick, Frederick, Maryland, United States of America

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  • Angela Carville,

    Affiliation: Department of Pathology, Harvard Medical School, New England Primate Research Center, Southborough, Massachusetts, United States of America

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  • Keith G. Mansfield,

    Affiliation: Department of Pathology, Harvard Medical School, New England Primate Research Center, Southborough, Massachusetts, United States of America

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  • Jeffrey D. Lifson,

    Affiliation: SAIC Frederick, National Cancer Institute at Frederick, Frederick, Maryland, United States of America

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  • Wenjun Li,

    Affiliation: University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Ronald C. Desrosiers,

    Affiliation: Department of Microbiology and Immunobiology, Harvard Medical School, New England Primate Research Center, Southborough, Massachusetts, United States of America

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  • R. Paul Johnson,

    Affiliations: Immunology Division, Harvard Medical School, New England Primate Research Center, Southborough, Massachusetts, United States of America, Ragon Institute of Massachusetts General Hospital, MIT, and Harvard, and Infectious Disease Unit, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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  • David T. Evans mail

    david_evans@hms.harvard.edu

    Affiliation: Department of Microbiology and Immunobiology, Harvard Medical School, New England Primate Research Center, Southborough, Massachusetts, United States of America

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  • Published: August 23, 2012
  • DOI: 10.1371/journal.ppat.1002890

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