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Research Article

Block of Death-Receptor Apoptosis Protects Mouse Cytomegalovirus from Macrophages and Is a Determinant of Virulence in Immunodeficient Hosts

  • Linda Ebermann,

    Affiliation: Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany

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  • Zsolt Ruzsics,

    Affiliation: Max von Pettenkofer Institute, Ludwig Maximilians University, Munich, Germany

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  • Carlos A. Guzmán,

    Affiliation: Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany

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  • Nico van Rooijen,

    Affiliation: Department of Molecular Cell Biology, Faculty of Medicine, Vrije University, Amsterdam, The Netherlands

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  • Rosaely Casalegno-Garduño,

    Affiliation: Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany

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  • Ulrich Koszinowski,

    Affiliation: Max von Pettenkofer Institute, Ludwig Maximilians University, Munich, Germany

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  • Luka Čičin-Šain mail

    Luka.Cicin-Sain@helmholtz-hzi.de

    Affiliations: Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany, Department of Virology, Hannover School of Medicine, Hannover, Germany

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  • Published: December 13, 2012
  • DOI: 10.1371/journal.ppat.1003062

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