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Research Article

MiniCD4 Microbicide Prevents HIV Infection of Human Mucosal Explants and Vaginal Transmission of SHIV162P3 in Cynomolgus Macaques

  • Nathalie Dereuddre-Bosquet,

    Affiliations: CEA, Division of Immuno-Virology, iMETI, Fontenay-aux Roses, France, Paris-Sud University, UMRE01, Orsay, France

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  • Laurence Morellato-Castillo,

    Affiliation: CEA, iBiTecS, Service d'Ingénierie Moléculaire des Protéines, Gif sur Yvette, France

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  • Joachim Brouwers,

    Affiliation: Katholieke Universiteit Leuven, Leuven, Belgium

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  • Patrick Augustijns,

    Affiliation: Katholieke Universiteit Leuven, Leuven, Belgium

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  • Kawthar Bouchemal,

    Affiliation: Paris-Sud University, Faculty of Pharmacy, Chatenay-Malabry, France

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  • Gilles Ponchel,

    Affiliation: Paris-Sud University, Faculty of Pharmacy, Chatenay-Malabry, France

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  • Oscar H. P. Ramos,

    Affiliation: CEA, iBiTecS, Service d'Ingénierie Moléculaire des Protéines, Gif sur Yvette, France

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  • Carolina Herrera,

    Affiliation: Section of Infectious Diseases, Faculty of Medicine, St Mary's Campus, Imperial College, London, United Kingdom

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  • Martha Stefanidou,

    Affiliation: Department of Pediatrics and Microbiology-Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America

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  • Robin Shattock,

    Affiliation: Section of Infectious Diseases, Faculty of Medicine, St Mary's Campus, Imperial College, London, United Kingdom

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  • Leo Heyndrickx,

    Affiliation: Institute of Tropical Medicine and University of Antwerp, Antwerp, Belgium

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  • Guido Vanham,

    Affiliation: Institute of Tropical Medicine and University of Antwerp, Antwerp, Belgium

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  • Pascal Kessler,

    Affiliation: CEA, iBiTecS, Service d'Ingénierie Moléculaire des Protéines, Gif sur Yvette, France

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  • Roger Le Grand,

    Affiliations: CEA, Division of Immuno-Virology, iMETI, Fontenay-aux Roses, France, Paris-Sud University, UMRE01, Orsay, France

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  • Loïc Martin mail

    loic.martin@cea.fr

    Affiliation: CEA, iBiTecS, Service d'Ingénierie Moléculaire des Protéines, Gif sur Yvette, France

    X
  • Published: December 06, 2012
  • DOI: 10.1371/journal.ppat.1003071

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