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Research Article

A Systems Biology Approach Reveals that Tissue Tropism to West Nile Virus Is Regulated by Antiviral Genes and Innate Immune Cellular Processes

  • Mehul S. Suthar,

    Affiliation: Department of Immunology, University of Washington School of Medicine, Seattle, Washington, United States of America

    Current address: Department of Pediatrics and Children's Healthcare of Atlanta, Emory Vaccine Center, Emory University, Atlanta, Georgia, United States of America.

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  • Margaret M. Brassil,

    Affiliation: Department of Immunology, University of Washington School of Medicine, Seattle, Washington, United States of America

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  • Gabriele Blahnik,

    Affiliation: Department of Immunology, University of Washington School of Medicine, Seattle, Washington, United States of America

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  • Aimee McMillan,

    Affiliation: Department of Immunology, University of Washington School of Medicine, Seattle, Washington, United States of America

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  • Hilario J. Ramos,

    Affiliation: Department of Immunology, University of Washington School of Medicine, Seattle, Washington, United States of America

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  • Sean C. Proll,

    Affiliation: Department of Microbiology, University of Washington School of Medicine, Seattle, Washington, United States of America

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  • Sarah E. Belisle,

    Affiliation: Department of Microbiology, University of Washington School of Medicine, Seattle, Washington, United States of America

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  • Michael G. Katze,

    Affiliation: Department of Microbiology, University of Washington School of Medicine, Seattle, Washington, United States of America

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  • Michael Gale Jr mail

    mgale@u.washington.edu

    Affiliations: Department of Immunology, University of Washington School of Medicine, Seattle, Washington, United States of America, Department of Microbiology, University of Washington School of Medicine, Seattle, Washington, United States of America

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  • Published: February 07, 2013
  • DOI: 10.1371/journal.ppat.1003168

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