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Research Article

Inflammasome Sensor NLRP1 Controls Rat Macrophage Susceptibility to Toxoplasma gondii

  • Kimberly M. Cirelli,

    Affiliation: Massachusetts Institute of Technology, Department of Biology, Cambridge, Massachusetts, United States of America

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  • Gezahegn Gorfu,

    Affiliation: Molecular Parasitology Section, Laboratory of Parasitic Diseases, NIAID, NIH, Bethesda, Maryland, United States of America

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  • Musa A. Hassan,

    Affiliation: Massachusetts Institute of Technology, Department of Biology, Cambridge, Massachusetts, United States of America

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  • Morton Printz,

    Affiliation: Department of Pharmacology, University of California-San Diego, La Jolla, California, United States of America

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  • Devorah Crown,

    Affiliation: Microbial Pathogenesis Section, Laboratory of Parasitic Diseases, NIAID, NIH, Bethesda, Maryland, United States of America

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  • Stephen H. Leppla,

    Affiliation: Microbial Pathogenesis Section, Laboratory of Parasitic Diseases, NIAID, NIH, Bethesda, Maryland, United States of America

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  • Michael E. Grigg mail,

    griggm@niaid.nih.gov (MEG); jsaeij@mit.edu (JPJS); mmoayeri@niaid.nih.gov (MM)

    Affiliation: Molecular Parasitology Section, Laboratory of Parasitic Diseases, NIAID, NIH, Bethesda, Maryland, United States of America

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  • Jeroen P. J. Saeij mail,

    griggm@niaid.nih.gov (MEG); jsaeij@mit.edu (JPJS); mmoayeri@niaid.nih.gov (MM)

    Affiliation: Massachusetts Institute of Technology, Department of Biology, Cambridge, Massachusetts, United States of America

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  • Mahtab Moayeri mail

    griggm@niaid.nih.gov (MEG); jsaeij@mit.edu (JPJS); mmoayeri@niaid.nih.gov (MM)

    Affiliation: Microbial Pathogenesis Section, Laboratory of Parasitic Diseases, NIAID, NIH, Bethesda, Maryland, United States of America

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  • Published: March 13, 2014
  • DOI: 10.1371/journal.ppat.1003927

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