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Research Article

Infection of Adult Thymus with Murine Retrovirus Induces Virus-Specific Central Tolerance That Prevents Functional Memory CD8+ T Cell Differentiation

  • Shiki Takamura mail,

    takamura@med.kindai.ac.jp (ST); masaaki@med.kindai.ac.jp (MM)

    Affiliation: Department of Immunology, Kinki University Faculty of Medicine, Osaka, Japan

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  • Eiji Kajiwara,

    Affiliation: Department of Immunology, Kinki University Faculty of Medicine, Osaka, Japan

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  • Sachiyo Tsuji-Kawahara,

    Affiliation: Department of Immunology, Kinki University Faculty of Medicine, Osaka, Japan

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  • Tomoko Masumoto,

    Affiliation: Department of Immunology, Kinki University Faculty of Medicine, Osaka, Japan

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  • Makoto Fujisawa,

    Affiliation: Department of Immunology, Kinki University Faculty of Medicine, Osaka, Japan

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  • Maiko Kato,

    Affiliation: Department of Immunology, Kinki University Faculty of Medicine, Osaka, Japan

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  • Tomomi Chikaishi,

    Affiliation: Department of Immunology, Kinki University Faculty of Medicine, Osaka, Japan

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  • Yuri Kawasaki,

    Affiliation: Department of Immunology, Kinki University Faculty of Medicine, Osaka, Japan

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  • Saori Kinoshita,

    Affiliation: Department of Immunology, Kinki University Faculty of Medicine, Osaka, Japan

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  • Manami Itoi,

    Affiliation: Department of Immunology and Microbiology, Meiji University of Integrative Medicine, Kyoto, Japan

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  • Nobuo Sakaguchi,

    Affiliation: Department of Immunology, Kumamoto University School of Medicine, Kumamoto, Japan

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  • Masaaki Miyazawa mail

    takamura@med.kindai.ac.jp (ST); masaaki@med.kindai.ac.jp (MM)

    Affiliation: Department of Immunology, Kinki University Faculty of Medicine, Osaka, Japan

    X
  • Published: March 20, 2014
  • DOI: 10.1371/journal.ppat.1003937

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