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Featured Opinion

Systematic Genetic Nomenclature for Type VII Secretion Systems

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Bitter et al. propose and introduce a systematic nomenclature with guidelines for name selection of new components that will greatly facilitate communication and understanding in the rapidly developing field of T7S systems.

 

Featured Research

TmpL, a Transmembrane Protein Required for Intracellular Redox Homeostasis and Virulence in a Plant and an Animal Fungal Pathogen

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Kim et al. describe a novel protein, TmpL, involved in development and virulence in both plant and animal pathogenic fungi. Their findings provide new insights into mechanisms underlying the complex web of interactions between reactive oxygen species (ROS) and cell differentiation for both plant and animal fungal pathogenesis.

 

A Quantitative RNAi Screen for JNK Modifiers Identifies Pvr as a Novel Regulator of Drosophila Immune Signaling

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David Bond and Edan Foley conduct a survey of the entire Drosophila genome for novel regulators in the Imd/dJNK pathway. The pair uncovers a novel link between the proliferative Pvr pathway and the IMD pathway.

 

Dynamics of HIV-1 Assembly and Release

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Ivanchenko et al. analyze the dynamics of HIV assembly and release making use of fluorescently labeled HIV structural proteins. The results add dynamic information to our picture of virus release and provide an experimental basis for interfering with this stage of virus replication.

 

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