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Featured Opinion

Pathogen Discovery

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Lipkin opines on the rate of pathogen discovery and the detail in resultant experiments, both of which have accelerated over the past two decades. He prescribes how to keep up, evaluates the efficacy of new technologies, and notes who scientists should look to for further data.

Image Credit: CDC

 

Featured Research

Conserved Mosquito/Parasite Interactions Affect Development of Plasmodium falciparum in Africa

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Mendes et al. identify specific A. gambiae genes that demonstrably regulate the density of mosquito infection by P. falciparum parasites circulating in malaria patients in Africa.

 

Targeting of Pseudorabies Virus Structural Proteins to Axons Requires Association of the Viral Us9 Protein with Lipid Rafts

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Lyman et al. add to their former work, which characterized the viral membrane protein Us9, determining exactly how and where the protein localizes to promote axonal targeting within cellular membranes.

 

The Uptake of Apoptotic Cells Drives Coxiella burnetii Replication and Macrophage Polarization: A Model for Q Fever Endocarditis

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Benoit et al. study C. burnetii and find that leukocyte apoptosis associated with valvulopathy may be critical for the pathogenesis of Q fever endocarditis.

 

PLoS Pathogens is an open-access journal that publishes important new ideas on bacteria, fungi, parasites, prions, and viruses that contribute to our understanding of the biology of pathogens and pathogen-host interactions.

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